Maybe its just me, but I really like biscuits and pocket joinery. Generally, for me they set up tight with clamps and titebond II and seem strong to boot. It's fast and easy. I use both for built-ins, face frames, and cabinet carcasses without any complaints yet.
However, if I'm going to be building a piece of furniture or something I'd like to be an heirloom piece I'm going to use M&T. If you're table is going to see moderate to heavy use, and you want to pass it down...M&T & angle brackets!
just my opinion.