After 50 years of sawdust making...
I use 2 mobile Jet 1100s DC units with very short flex hose attached. This minimizes the loss due to the flex hose. I leave different length 4" flex hoses attached to the machines I use most often and move the DC over to them as needed. My machines include a 6" jointer and several 12" tables saws hooked to one DC. The other DC shares between a 24" dual drum and a 12"drum sander and a 15" planer. All other tools are hooked to 16 gal. Rigid shop vacs all around the shop sorta tucked into corners or under tables. These include 14" bandsaws, a 12" RAS, and several router tables. For small random orbit or belt sanders. I connect them to the dust ports with a lightweight flex hose 1 1/4" used for dry wall sanding. It works great!
Overhead, I use a Jest AFS 1000 air filter to get the airborne dust which is much finer. I don't wear a mask as a rule but have on occasion. This system works well for me with one exception, the table saw. Older contractor saws and some motorized saws like I have do NOT have a blade shroud designed to collect the dust like the newer saws, Bosch 4000-09 and others. If your table saw has a dust shroud, count your blessings. If not, enclose the bottom and seal off the openings enough to allow cooling air, but to increase the airflow velocity. I have done this with some success.
Good luck, but post this in Dust Collection and you will get more replies.
The answer to your question will only be as detailed and specific as the question is detailed and specific. Good questions also include a sketch or a photo that illustrates your issue. (:< D)