Personally, I have a great distaste for things made with pocket screws. I would avoid them at all cost. I can maybe see commercial people using them for cheap projects, but for projects for myself or my friends, I would never use them.
Perhaps that is just me, and perhaps this not relevant. Please feel free to disregard this comment.
I watched my neighbor construct a dining table and benches, a living room TV stand, and a bookcase for his daughter, all in one afternoon. He used construction lumber (2x4s, 2x6s, and 4x4s), a miter saw, and pocket screws. No real measuring, no glue, no muss, no fuss. There was not much sanding or finish. No attempt was made to orient or mount the boards to hide the milling stamps. (For that matter, no attempt was made to design for future wood movement, either.)
The furniture was primitive, but reasonably sturdy. The daughter had not given any real notice that she was moving out, but the furniture was done and ready in an afternoon. I was not impressed with the look of the furniture, but I was very impressed with the efficiency with which it was made and its suitability to purpose.
When all was said and done, I felt bad about how I felt while he was constructing it. I praised his work and woodworking skills appropriately, but in my own mind, I was silently critical about his use of pocket screws, the lack of glue, proper joinery, or proper finish, the lack of consideration for wood movement, and the overall crudeness and primitiveness of it all.
Later, thinking about it more, I felt that I had unfairly judged him. He had delivered exactly what his "customer" wanted, in blazingly fast time, at ultra-low cost. The thick construction lumber made it strong and sturdy. He was very efficient. He could build entire suites of furniture in the time it takes me to plan one cut.
So ... I continually strive to keep an open mind, and that should include pocket screws. I don't use them on principle, but that shouldn't stop me, because I have no principles. ;-)